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Learn more about Dr Gibson's research with ZAP70 1.Reviewer for manuscripts for peer-reviewed scientific journal: Oncogene, Molecular Biology of the Cell, Blood, Cancer, Cancer Research, British Journal of Cancer, Clinical Cancer Research, Molecular Cancer Therapeutics, Molecular Pharmacology, EMBO, BLOOD, Autophagy, Free Radical Biology and Medicine, Cell Death and Differentiation and Carcinogenesis 2.
We are currently investigating the regulatory elements controlling Mcl-1 expression.
Molecular-based therapies could alter the balance between cell death and survival towards killing cancer cells.
One protein important in the regulation of cell death is the Bcl-2 BH-3 only member BNIP3.
BNIP3 expression is induced under low oxygen (hypoxia) conditions and is over expressed in solid tumours in hypoxic regions.
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